VDR Haploinsufficiency Impacts Body Composition and Skeletal Acquisition in a Gender-Specific Manner
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چکیده
منابع مشابه
Serum IGF-1 Affects Skeletal Acquisition in a Temporal and Compartment-Specific Manner
Insulin-like growth factor-1 (IGF-1) plays a critical role in the development of the growing skeleton by establishing both longitudinal and transverse bone accrual. IGF-1 has also been implicated in the maintenance of bone mass during late adulthood and aging, as decreases in serum IGF-1 levels appear to correlate with decreases in bone mineral density (BMD). Although informative, mouse models ...
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Aging is associated with decreases in aerobic capacity, cardiac function, and insulin sensitivity as well as alterations in myocardial substrate metabolism. Endurance exercise training (EET) improves cardiac function in a gender-specific manner, and EET has been shown to improve whole body glucose tolerance, but its effects on myocardial metabolism are unclear. Accordingly, we studied the effec...
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Aging is associated with decreases in aerobic capacity, cardiac function, and insulin sensitivity as well as alterations in myocardial substrate metabolism. Endurance exercise training (EET) improves cardiac function in a gender-specific manner, and EET has been shown to improve whole-body glucose tolerance, but its effects on myocardial metabolism are unclear. Accordingly, we studied the effec...
متن کاملThyroid Hormones Regulate Zebrafish Melanogenesis in a Gender-Specific Manner
Zebrafish embryos are treated with anti-thyroidal compounds, such as phenylthiourea, to inhibit melanogenesis. However, the mechanism whereby the thyroidal system controls melanin synthesis has not been assessed in detail. In this work, we tested the effect of the administration of diets supplemented with T3 (500μg/g food) on the pigment pattern of adult zebrafish. Oral T3 induced a pronounced ...
متن کاملBody composition analysis to determine gender specific physical fitness equations in a cohort of Saudi population
OBJECTIVE To determine an association between body composition analysis and physical fitness in the Saudi population and derive gender specific physical fitness equations. METHODS A total of 530 healthy Saudi adults aged 15-72 years (mean 37.16±14.12 years) were enrolled in this study. Body composition analysis was assessed by bioelectrical impedance analysis (BIA), with a commercially availa...
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ژورنال
عنوان ژورنال: Calcified Tissue International
سال: 2011
ISSN: 0171-967X,1432-0827
DOI: 10.1007/s00223-011-9505-1